Researchers Unveil experimental Blood Cancer Therapy with Exciting Results

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An experimental therapy that harnesses the power of the immune system is showing remarkable success in the fight against some of the mostly deadly blood cancers.

The work, headed up by Stanley Riddell, a researcher at the Fred Hutchinson Cancer Research Center in the U.S. state of Washington, involves engineering the patient's immune system T-cells and has shown considerable promise in small clinical trials.

In one study of 35 patients with acute lymphoblastic leukemia, or ALL, 94 percent experienced a complete remission. Fifty to 80 percent of patients with other blood cancers, including non-Hodgkin's lymphoma, also saw a reduction in symptoms.

"So, this is encouraging because these are all patients who have failed all conventional therapies, including many kinds of bone marrow and stem cell transplants,? Riddell said. ?So these patients really do not have any other treatment options that are likely to put them into remission. So, getting these very high rates of remission is obviously very exciting for us."

Immune system T-cells, which usually fight invading viruses and bacteria, can also mount a response to cancer, but they are soon overwhelmed by the disease.